Setting a trap for respiratory viruses

Setting the TRAP for central leptin targets

In this issue of Molecular Metabolism, Allison and her colleagues break new ground in our understanding of CNS leptin physiology [1]. By applying the sophisticated Translating Ribosome Affinity Purification (TRAP) technique in combination with RNA sequencing (TRAP-seq), they succeed in identifying novel markers for hypothalamic and brainstem subpopulations of leptin receptor (LepRb)-positive ne...

Surveillance for emerging respiratory viruses.

Several new viral respiratory tract infectious diseases with epidemic potential that threaten global health security have emerged in the past 15 years. In 2003, WHO issued a worldwide alert for an unknown emerging illness, later named severe acute respiratory syndrome (SARS). The disease caused by a novel coronavirus (SARS-CoV) rapidly spread worldwide, causing more than 8000 cases and 800 deat...

Predictive value of testing nasopharyngeal samples for respiratory viruses in the setting of lower respiratory tract disease.

To determine the predictive value of nasopharyngeal (NP) sample testing for respiratory viruses (RVs) in suspected lower respiratory tract disease, 72 paired NP and bronchoalveolar lavage (BAL) fluid specimen sets, mostly from transplant recipients or patients with hematologic malignancies, were analyzed. Overall, 31.3% of the specimens tested positive for an RV. In 19 sets (26.4%), the NP and ...

A new Overlay for Plaquing Animal Viruses

Trap E-mail Address for Combating E-mail Viruses

The biggest infection events show that the most dangerous viruses propagate via the Internet email systems. We propose a new solution to accelerate the identification of infected computers after an attack by e-mail viruses. Our approach uses trap e-mail addresses secured by a feasible cryptographic technique. The novelty of our work is the introduction of virtual e-mail addresses to identify vi...